MM-206 是一种STAT3活性抑制剂,有效抑制 STAT3 SH2 结构域-磷酸肽相互作用,IC50为 1.2 μM。MM-206 在急性髓性白血病 (AML) 细胞系中表现出剂量依赖性诱导细胞凋亡。
生物活性 | MM-206, aSTAT3activity inhibitor, potently inhibits theSTAT3SH2 domain-phosphopeptide interaction withIC50of 1.2 μM. MM-206 demonstrates dose-dependent induction ofapoptosisin acute myeloid leukemia (AML) cell lines[1]. |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |