FLT3/ITD-IN-1 (Compound 1) 是一种有效的FLT3-ITD抑制剂,对FLT3和 FLT3-ITD 的IC50值分别为 38.2 nM 和 144.1 nM。FLT3/ITD-IN-1 对急性髓系白血病细胞具有良好的抗增殖活性。
生物活性 | FLT3/ITD-IN-1 (Compound 1) is a potentFLT3internal tandem duplications (FLT3-ITD) inhibitor withIC50values of 38.2 nM and 144.1 nM againstFLT3and FLT3-ITD, respectively. FLT3/ITD-IN-1 displays excellent antiproliferative activities against acute myeloid leukemia cell lines[1]. |
IC50& Target | IC50: 38.2 nM (FLT3), 144.1 nM (FLT3-ITD)[1] |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |