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Steroid sulfatase-IN-4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Steroid sulfatase-IN-4图片
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Steroid sulfatase-IN-4 (Compound 16) 是一种不可逆的类固醇硫酸酯酶 (STS) 抑制剂,对人 STS 的IC50为 25 nM,可用于子宫内膜异位的研究。
生物活性

Steroid sulfatase-IN-4 (Compound 16) is an irreversiblesteroid sulfatase(STS) inhibitor with anIC50of 25 nM against human STS. Steroid sulfatase-IN-4 can be used for the research of endometriosis[1].

IC50& Target

IC50: 25 nM (hSTS in cellular assays)[1]

体外研究
(In Vitro)

Steroid sulfatase-IN-4 (Compound 16) shows good metabolic stability in human hepatic S9 fraction and low intrinsic clearance Clint (<30 μlminmg protein)[1].
Steroid sulfatase-IN-4 (20 μM; 24 h) shows cytotoxicity for HEK-293 cells (53.6% inhibition)[1].
Steroid sulfatase-IN-4 (1 μM) shows 25% inhibition against human 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) in a cell-free assay[1].

分子量

420.87

Formula

C19H17ClN2O5S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.