Steroid sulfatase -IN-2 is an activesteroid sulfatase (STS)inhibitor with anIC₅₀value of 109.5 nM. Steroid sulfatase-IN-2 can be used for the research of hormone-dependent cancers, such as estrogen-dependent breast and endometrialcancer^[1].

IC50：109.5 nM (STS)^[1]

Steroid sulfatase-IN-2 (compound 1h, 0.001-10 μM, 1 h) inhibits STS in the lysate of JEG-3 cells, with an IC₅₀value of 109.5 nM^[1].
Steroid sulfatase-IN-2 (1-1 μM, 20 h) inhibits STS in a whole-cell assay against JEG-3 cells, with an IC₅₀value of 13.6 nM^[1].
Steroid sulfatase-IN-2 (0.01-100 μM, 5 days) shows dose-dependent antiproliferative activity against T-47D estrogen-dependent breast cancer cells^[1].

350.43

C₁₇H₂₂N₂O₄S

2413880-39-2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.