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Steroid sulfatase-IN-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Steroid sulfatase-IN-2图片
CAS NO:2413880-39-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Steroid sulfatase-IN-2 是一种有活性的类固醇硫酸酯酶 (STS) 抑制剂,IC50值为 109.5 nM。Steroid sulfatase-IN-2 可用于激素依赖性癌症的研究,如雌激素依赖性乳腺癌和子宫内膜癌。
生物活性

Steroid sulfatase -IN-2 is an activesteroid sulfatase (STS)inhibitor with anIC50value of 109.5 nM. Steroid sulfatase-IN-2 can be used for the research of hormone-dependent cancers, such as estrogen-dependent breast and endometrialcancer[1].

IC50& Target

IC50:109.5 nM (STS)[1]

体外研究
(In Vitro)

Steroid sulfatase-IN-2 (compound 1h, 0.001-10 μM, 1 h) inhibits STS in the lysate of JEG-3 cells, with an IC50value of 109.5 nM[1].
Steroid sulfatase-IN-2 (1-1 μM, 20 h) inhibits STS in a whole-cell assay against JEG-3 cells, with an IC50value of 13.6 nM[1].
Steroid sulfatase-IN-2 (0.01-100 μM, 5 days) shows dose-dependent antiproliferative activity against T-47D estrogen-dependent breast cancer cells[1].

Cell Viability Assay[1]

Cell Line:T-47D cells
Concentration:0.01-100 μM
Incubation Time:5 days
Result:Inhibited cell proliferation with an IC50value of 5.78 μM.
分子量

350.43

Formula

C17H22N2O4S

CAS 号

2413880-39-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.