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Ceftibuten
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Ceftibuten图片
CAS NO:97519-39-6
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议
100mg电议

产品介绍
头孢布烯 (Sch39720) 是一种抗生素，是一种口服活性头孢菌素，在体外对多种革兰氏阴性和某些革兰氏阳性病原体具有有效活性。
Cas No.97519-39-6
别名头孢布烯; Sch 39720
化学名(6R,7R)-7-((Z)-((Z)-4-carboxy-1-hydroxy-2-(2-imino-2,3-dihydrothiazol-4-yl)but-2-en-1-ylidene)amino)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Canonical SMILESN=C1NC(C(/C(O)=N/[C@]([C@]2([H])N3C(C(O)=O)=CCS2)([H])C3=O)=C([H])/CC(O)=O)=CS1
分子式C15H14N4O6S2
分子量410.42
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Ceftibuten(Sch39720) is a third-generation cephalosporin antibiotic.IC50:Target: AntibacterialCeftibuten displayed high activity against Haemophilus influenzae and Branhamella catarrhalis. There was reduced activity against Streptococcus pneumoniae (MIC90 16 mg/l). The protein binding of Ceftibuten was 77% and the primary target site PBP 3. A high degree of stability to beta-lactamase hydrolysis was observed. [1]

References:
[1]. Wise R, et al. Ceftibuten--in-vitro activity against respiratory pathogens, beta-lactamase stability and mechanism of action. J Antimicrob Chemother, 1990. 26(2): p. 209-213.