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Pioglitazone-d4(alkyl)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pioglitazone-d4(alkyl)图片
CAS NO:1134163-31-7
包装:1mg

产品名称
吡格列酮 d4 (alkyl)
产品介绍
Pioglitazone-d4 (alkyl) 是 Pioglitazone 的氘代物。Pioglitazone (U 72107) 是一种有效的选择性PPARγ激动剂,高亲和力结合到 PPARγ 配体结合域。作用于人和鼠 PPARγ,EC50分别为 0.93 和 0.99 μM。
生物活性

Pioglitazone-d4 (alkyl) (U 72107-d4 (alkyl)) is the deuterium labeled Pioglitazone. Pioglitazone (U 72107) is a potent and selectivePPARγagonist with high affinity binding to thePPARγligand-binding domain withEC50of 0.93 and 0.99 μM for human and mousePPARγ, respectively[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

360.46

Formula

C19H16D4N2O3S

CAS 号

1134163-31-7

中文名称

吡格列酮 d4 (alkyl)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.