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Fenofibrate-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Fenofibrate-d6图片
CAS NO:1092484-56-4
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
非诺贝特 d6
产品介绍
Fenofibrate-d6 是 Fenofibrate 的氘代物。Fenofibrate 是一种选择性的PPARα激动剂,EC50为 30 μM。Fenofibrate 抑制细胞色素 P450 亚型, 对CYP2C19CYP2B6CYP2C9CYP2C8CYP3A4IC50分别为 0.2,0.7,9.7,4.8 和 142.1 μM。
生物活性

Fenofibrate-d6 is the deuterium labeled Fenofibrate. Fenofibrate is a selectivePPARαagonist with anEC50of 30 μM. Fenofibrate also inhibits humancytochrome P450isoforms, withIC50s of 0.2, 0.7, 9.7, 4.8 and 142.1 μM forCYP2C19,CYP2B6,CYP2C9,CYP2C8, andCYP3A4, respectively.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

366.87

Formula

C20H15D6ClO4

CAS 号

1092484-56-4

中文名称

非诺贝特 d6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.