CAS NO: | 213411-83-7 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Edaglitazone is a potent, selective and orally activePPARγagonist, withEC50s of 35.6 nM and 1053 nM forPPARαandPPARγ, respectively. Edaglitazone displays antiplatelet, antidiabetic and anti-hyperglycemic activity[1][2][3]. | ||
IC50& Target[1] |
| ||
体外研究 (In Vitro) | Edaglitazone (3-16 μM; 5 min) inhibits the collagen (1.2 μg/mL)-induced platelet aggregation. Edaglitazone increases the intraplatelet levels of cAMP in a concentration dependent manner. Edaglitazone preventes the Collagen-induced intraplatelet levels of PPARγ decrease[3]. | ||
体内研究 (In Vivo) | Edaglitazone (4.4 mg/kg; p.o. daily for 10 days) enhances insulin sensitivity in obese rats[2]. | ||
分子量 | 464.56 | ||
Formula | C24H20N2O4S2 | ||
CAS 号 | 213411-83-7 | ||
中文名称 | 依格列宗 | ||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |