| CAS NO: | 2398-96-1 |
| 包装 | 价格(元) |
| 10mM (in 1mL DMSO) | 电议 |
| 50mg | 电议 |
| Cas No. | 2398-96-1 |
| 别名 | 托萘酯; NP-27 |
| 化学名 | O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate |
| Canonical SMILES | CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2 |
| 分子式 | C19H17NOS |
| 分子量 | 307.41 |
| 溶解度 | ≥ 12.7mg/mL in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Tolnaftate (NP-27) is a synthetic thiocarbamate used as an anti-fungal agent. . Tolnaftate (NP-27) blocked sterol biosynthesis in fungal cells and cell extracts, with accumulation of squalene. This point of action was confirmed by the direct inhibition of microsomal squalene epoxidase from Candida albicans[1]. Tolnaftate (NP-27) inhibited sterol biosynthesis, At 100 microM, tolnaftate caused up to a 30% release of intracellular [14C]aminoisobutyric acid[2]. References: |
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