CAS NO: | 88898-17-3 |
包装: | 1mg |
市场价: | 2510元 |
Cas No. | 88898-17-3 |
别名 | 心钠肽,Atrial natriuretic factor (1-28) (rat) |
化学名 | (1Z,3S,4Z,6S,7Z,9S,10Z,12S,13Z,15S)-1-((4R,5Z,8Z,10S,11Z,14E,16S,17Z,19S,20Z,22S,23Z,26Z,28S,29Z,31S,32Z,34S,35Z,37S,38Z,40S,41Z,44Z,47Z,49S,50E,52R)-52-((Z)-((2S,3Z,5S,6Z,8S,9Z,11S,12Z,14S,15Z,17S)-17-amino-8,11-bis(3-guanidinopropyl)-1,4,7,10,13,16,18-h |
Canonical SMILES | CC[C@]([C@@]1([H])/C(O)=N/C/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N\C/C(O)=N/[C@@](/C(O)=N/C/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](C(O)=O)([H])CC2=CC=C(O)C=C2)([H])CCCNC(N)=N)([H])CC3=CC=CC=C3)([H])CO) |
分子式 | C128H205N45O39S2 |
分子量 | 3062.43 |
溶解度 | Soluble in Water |
储存条件 | Desiccate at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Atrial Natriuretic Peptide (ANP) (1-28), rat is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner. Rat ANP (1-28) and rat BNP-45, which are the respective major circulating forms of ANP and BNP in rats, potently inhibited Ang II-stimulated endothelin-1 secretion in a concentration-dependent manner. Rat ANP (5-25) is less effective that Rat ANP(1-28) with respect to inhibiting immunoreactive (ir)-endothelin-1 secretion and increasing cellular cyclic GMP. Rat ANP (1-28) inhibits the secretion of ir-endothelin-1 in a concentration-dependent manner between 0.01 and 1 μM[1]. References: |