Ac-RYYRWK-NH2 是一种有效的、选择性的伤害感受素受体 (NOP) 部分激动剂,[3H]Ac-RYYRWK-NH2 与大鼠皮质膜 ORL1 结合,Kd 为 0.071 nM,但对 μ-, κ 没有亲和力- 或 δ-阿片受体。
Cas No. | 200959-47-3 |
化学名 | (S)-2-((Z)-((6S,7Z,9S,10Z,12S,13Z,15S,16Z,18S)-18-((1H-indol-3-yl)methyl)-1-amino-15-(3-guanidinopropyl)-7,10,13,16,19-pentahydroxy-9,12-bis(4-hydroxybenzyl)-6-((Z)-(1-hydroxyethylidene)amino)-1-imino-2,8,11,14,17-pentaazanonadeca-7,10,13,16-tetraen-19-yl |
Canonical SMILES | C/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](/C(O)=N/[C@@](C(O)=N)([H])CCCCN)([H])CC1=CNC2=CC=CC=C12)([H])CCCNC(N)=N)([H])CC3=CC=C(O)C=C3)([H])CC4=CC=C(O)C=C4)([H])CCCNC(N)=N |
分子式 | C49H69N15O9 |
分子量 | 1012.17 |
溶解度 | Soluble to 1 mg/ml in Water |
储存条件 | Desiccate at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |