CAS NO: | 1699717-32-2 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | BAY-545 is a potent and selectiveA2Badenosine receptorantagonist, with anIC50of 59 nM. BAY-545 also exhibitsIC50s of 66, 400, 280 nM for human, mouse, rat A2Badenosine receptorin cells, respectively, and aKiof 97 nM for human A2Badenosine receptor, with more selectivity over A1, A2A, and A3adenosine receptor[1]. | ||||||||||||||||
IC50& Target | IC50: 59 nM (A2Badenosine receptor), 66 nM (Human A2Badenosine receptor), 400 nM (Mouse A2Badenosine receptor), 280 nM (Rat A2Badenosine receptor), 1300 nM (Human A1adenosine receptor), 820 nM (Human A2Aadenosine receptor), 470 nM (Mouse A2Aadenosine receptor) and 750 nM (Rat A2Aadenosine receptor)[1] | ||||||||||||||||
体外研究 (In Vitro) | BAY-545 is selective at A2Badenosine receptor over A1, A2A, and A3adenosine receptor, with IC50s of 1300 nM (Human A1adenosine receptor), 820 nM (Human A2Aadenosine receptor), 470 nM (Mouse A2Aadenosine receptor) and 750 nM (Rat A2Aadenosine receptor)[1]. | ||||||||||||||||
分子量 | 433.45 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C18H22F3N3O4S | ||||||||||||||||
CAS 号 | 1699717-32-2 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : ≥ 150 mg/mL(346.06 mM) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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