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(+)-Valencene
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
(+)-Valencene图片
CAS NO:4630-07-3
包装与价格：
包装价格(元)
1g电议
5g电议

产品介绍

(+)-Valencene is a sesquiterpene that has been found in C.

Cas No.4630-07-3
别名巴伦西亚橘烯,NSC 148969
化学名(1R,7R,8aS)-1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-naphthalene
Canonical SMILESCC([C@@H]1CCC2=CCC[C@@H](C)[C@]2(C)C1)=C
分子式C15H24
分子量204.4
溶解度Slightly soluble in water
储存条件Store at 4℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

(+)-Valencene is a sesquiterpene that has been found in C. sativa and is an aromatic component of orange essence oil.[1],[2] (+)-Valencene (50 μM) induces heme oxgenase-1 (HO-1) expression in macrophages and inhibits the expression of inducible nitric oxide synthase (iNOS), the production of nitric oxide (NO), and the release of high-mobility group box-1 (HMGB1) in RAW 264.7 cells stimulated with LPS.[3] It also increases the survival rate in a mouse model of sepsis induced by cecal ligation and puncture. (+)-Valencene has been used in the synthesis of nootkatone.[4]

Referece:
[1]. Naz, S., Hanif, M.A., Bhatti, H.N., et al. Impact of supercritical fluid extraction and traditional distillation on the isolation of aromatic compounds from Cannabis indica and Cannabis sativa. J. Essent. Oil Bearing Plants 20(1), 175-184 (2017).
[2]. Hognadóttir , A., and Rouseff, R.L. Identification of aroma active compounds in orange essence oil using gas chromatography-olfactometry and gas chromatography-mass spectrometry. J. Chromatogr. A. 998(1-2), 201-211 (2003).
[3]. Tsoyi, K., Jang, H.J., Lee, Y.S., et al. (+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction. J. Ethnopharmacol. 137(3), 1311-1317 (2011).
[4]. Kolwek, J., Behrens, C., Linke, D., et al. Cell-free one-pot conversion of (+)-valencene to (+)-nootkatone by a unique dye-decolorizing peroxidase combined with a laccase from Funalia trogii. J. Ind. Microbiol. Biotechnol. 45(2), 89-101 (2018).