S1PR1 modulator1 is a selectiveS1PR1inhibitor, with apIC₅₀of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4^[1].

pIC50: 7.6 (S1PR1), 6 (S1PR3)^[1]

S1PR1 modulator 1 (Compound 10a; (Z,Z)-10a) is selective at S1PR1 over S1PR3 (pIC₅₀, 6), S1PR2 and S1PR4 (pIC₅₀s,<5)^[1].

408.51

C₂₃H₂₄N₂O₃S

2328109-05-1

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.