CAS NO: | 63-75-2 |
包装 | 价格(元) |
10mg | 电议 |
50mg | 电议 |
生物活性 | Arecoline, a naturally occurring psychoactive alkaloid, is a partial agonist ofnicotinicandmuscarinic acetylcholine receptor. Arecoline exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline also can induce oxidative stress[1][2][3][4]. |
IC50& Target | nAChR/mAChR[3] |
体外研究 (In Vitro) | Arecoline induces the generation of reactive oxygen species and cell cycle arrest at the G1/G0 phase in HaCaT cells without affecting the expression of p21/Cip1. Arecoline-induced epithelial cell death at higher concentrations is caused by oxidative trauma without eliciting apoptosis. Arecoline upregulates the expression of the following stress-responsive genes: hemeoxygenase-1; ferritin light chain; glucose-6-phosphate dehydrogenase; glutamatecysteine ligase catalytic subunit; and glutathione reductase[1]. |
分子量 | 155.19 |
Formula | C8H13NO2 |
CAS 号 | 63-75-2 |
中文名称 | 槟榔碱 |
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |