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Arecoline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Arecoline图片
CAS NO:63-75-2
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品名称
槟榔碱
产品介绍
Arecoline,一种天然生物碱,是烟碱和毒蕈碱乙酰胆碱受体的部分激动剂。Arecoline 具有刺激、警觉、抗焦虑和抗寄生虫作用。Arecoline 也可以诱导氧化应激。
生物活性

Arecoline, a naturally occurring psychoactive alkaloid, is a partial agonist ofnicotinicandmuscarinic acetylcholine receptor. Arecoline exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline also can induce oxidative stress[1][2][3][4].

IC50& Target

nAChR/mAChR[3]

体外研究
(In Vitro)

Arecoline induces the generation of reactive oxygen species and cell cycle arrest at the G1/G0 phase in HaCaT cells without affecting the expression of p21/Cip1. Arecoline-induced epithelial cell death at higher concentrations is caused by oxidative trauma without eliciting apoptosis. Arecoline upregulates the expression of the following stress-responsive genes: hemeoxygenase-1; ferritin light chain; glucose-6-phosphate dehydrogenase; glutamatecysteine ligase catalytic subunit; and glutathione reductase[1].

分子量

155.19

Formula

C8H13NO2

CAS 号

63-75-2

中文名称

槟榔碱

结构分类
  • Alkaloids
  • Piperidine Alkaloids
来源
  • Plants
  • Palmae
  • Areca catechuL.
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.