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Tasimelteon-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tasimelteon-d5图片
CAS NO:1962124-51-1
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
BMS-214778-d5
VEC-162-d5
产品介绍
Tasimelteon-d5 (BMS-214778-d5) 是 Tasimelteon 的氘代物。Tasimelteon (BMS-214778) 是一种具有口服活性,选择性的双重褪黑激素受体激动剂 (DMRA)。Tasimelteon 对 MT2 受体的亲和力是 MT1 受体的 2.1-4.4 倍。Tasimelteon 是一种昼夜节律性调节剂,具有用于非 24 小时睡眠/觉醒障碍 (Non-24) 的潜力。
生物活性

Tasimelteon-d5 (BMS-214778-d5) is the deuterium labeled Tasimelteon. Tasimelteon (BMS-214778) is an orally active and selectivedualmelatonin receptor agonist(DMRA). Tasimelteon has 2.1-4.4 times greater affinity for theMT2receptor than for theMT1receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24)[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

250.35

Formula

C15H14D5NO2

CAS 号

1962124-51-1

中文名称

他司美琼 d5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.