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DFMTI
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
DFMTI图片
CAS NO:864864-86-8
包装与价格:
包装价格(元)
10 mM * 1 mL in DMSO电议
1mg电议
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品名称
MK5435
产品介绍
DFMTI能够完全阻止rmGlu1 L757V谷氨酸反应。
生物活性

DFMTI can completely block the rmGlu1 L757V glutamate response. In vitro: DFMTI can completely block the rmGlu1 L757V glutamate response, although significantly higher concentrations were required to induce blockade. In vivo: DFMTI is efficacious in disrupting prepulse inhibition when dosed orally in rats. DFMTI exhibits a moderate decrease in human potency of approximately 3-fold when compared to rat, exemplified by DFMTI.

IC50& Target

mGluR1

 

分子量

368.38

性状

Solid

Formula

C20H18F2N4O

CAS 号

864864-86-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month
溶解性数据
In Vitro: 

DMSO : 25 mg/mL(67.86 mM;ultrasonic and warming and heat to 60℃)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM2.7146 mL13.5729 mL27.1459 mL
5 mM0.5429 mL2.7146 mL5.4292 mL
10 mM0.2715 mL1.3573 mL2.7146 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。