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Prasugrel(Maleic acid)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Prasugrel(Maleic acid)图片
CAS NO:389574-20-3
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
马来酸普拉格雷
PCR 4099 (Maleic acid)
产品介绍
Prasugrel (PCR 4099) Maleic acid,一种噻吩吡啶和前药,抑制血小板功能。Prasugrel Maleic acid 是一种有效的P2Y12受体拮抗剂,抑制 ADP 诱导的血小板聚集。
生物活性

Prasugrel (PCR 4099) Maleic acid is a thienopyridine and prodrug, inhibits platelet function. Prasugrel Maleic acid is an orally active and potentP2Y12receptor antagonist, and inhibits ADP-induced platelet aggregation[1].

IC50& Target

P2Y12 receptor[1]

体外研究
(In Vitro)

In rat platelets, Prasugrel (PCR 4099) Maleic acid active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50value of 1.8 μM[2].
Prasugrel (PCR 4099) Maleic acid acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel (PCR 4099) Maleic acid is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h[1].

Clinical Trial
分子量

489.51

Formula

C24H24FNO7S

CAS 号

389574-20-3

中文名称

马来酸普拉格雷

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.