KRAS G12C inhibitor 44 (compound 54) 是一种有效且具有口服活性的KRAS G12C抑制剂。KRAS G12C inhibitor 44 在 MIA PaCA-2、H358 细胞中显示出抗增殖活性,IC50s 分别为 0.016,0.028 μM。KRAS G12C inhibitor 44 在体内显示出抗肿瘤作用。
生物活性 | KRAS G12C inhibitor 44 (compound 54) is a potent and orally activeKRAS G12Cinhibitor. KRAS G12C inhibitor 44 shows anti-proliferation activities with IC50s of 0.016, 0.028 μM in MIA PaCA-2, H358 cells, respectively. KRAS G12C inhibitor 44 shows antitumor effects in vivo[1]. |
IC50& Target[1] | |
分子量 | |
Formula | |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |