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Felypressin acetate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Felypressin acetate图片
CAS NO:914453-97-7
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品名称
PLV-2 acetate
产品介绍
Felypressin acetate (PLV-2 acetate) 是一种非儿茶酚胺的血管收缩剂,也是一种加压素 1 (vasopressin 1) 激动剂。Felypressin acetate 广泛用于牙科手术中。
生物活性

Felypressin acetate (PLV-2 acetate) is a non-catecholamine vasoconstrictor and avasopressin 1agonist. Felypressin acetate is widely used in dental procedures[1][2].

IC50& Target

Vasopressin 1[2]

体外研究
(In Vitro)

Felypressin is a synthetic hormone of the posterior pituitary lobe characterized by vasoconstrictor properties that is widely used in dental procedures. The vasoconstrictor action of Felypressin seems to be mediated by V1 receptors of the blood vessel smooth muscle cells[1].

体内研究
(In Vivo)

Felypressin can reduce toxicity during dental procedures. Felypressin increases the diastolic blood pressure of hypertensive patients with controlled blood pressure[1].
Cardiovascular effects of Felypressin (240 ng/kg; intravenous injection) are studied in Wistar rats. Felypressin induces a pressor effect. Felypressin depends on V1 receptors to induce pressor and bradycardic effects, and that it produces a high relationship between bradycardia and mean arterial pressure variation depending on area postrema and central V1 receptors[2].

Clinical Trial
性状

Solid

Formula

C46H65N13O11S2.xC2H4O2

CAS 号

914453-97-7

Sequence

Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6)

Sequence Shortening

CFFQNCPKG-NH2 (Disulfide bridge: Cys1-Cys6)

中文名称

醋酸苯赖加压素

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Protect from light, stored under nitrogen

Powder-80°C2 years
-20°C1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

溶解性数据
In Vitro: 

H2O : 100 mg/mL(Need ultrasonic)