CAS NO: | 55476-47-6 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | PSB-12062 is a potent and selectiveP2X4antagonist with anIC50of 1.38 μM for human P2X4. | ||||||||||||||||
IC50& Target | IC50: 1.38 μM (human P2X4), 92.8 nM (rat P2X4), 1.76 μM (mouse P2X4)[1] | ||||||||||||||||
体外研究 (In Vitro) | PSB-12062 shows similar potency in human, rat, and mouse species. PSB-12062 shows to be allosteric in nature with a 35-fold selectivity toward P2X4 versus P2X1, P2X2, P2X3, and P2X7. However, PSB-12062 is unable to completely block ATP-induced P2X4-mediated calcium influx even when used at high concentrations (>30 μM)[1]. | ||||||||||||||||
分子量 | 337.39 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C19H15NO3S | ||||||||||||||||
CAS 号 | 55476-47-6 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 25 mg/mL(74.10 mM;Need ultrasonic) 配制储备液
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