CAS NO: | 217087-09-7 |
包装 | 价格(元) |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
生物活性 | Esomeprazole magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a potent and orally activeH+, K+-ATPaseinhibitor. Esomeprazole magnesium trihydrate has the potential for upper intestinal disorders and gastroesophageal reflux disease research[1][2]. Esomeprazole magnesium trihydrate acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases[4]. | ||||||||||||||||
IC50& Target | H+, K+-ATPase[1] | ||||||||||||||||
体外研究 (In Vitro) | Esomeprazole magnesium trihydrate is develped from Esomeprazole strontium tetrahydrate (EST). EST contains esomeprazole, the S-enantiomer of omeprazole a salt-exchanged version of Esomeprazole magnesium trihydrate[2]. | ||||||||||||||||
体内研究 (In Vivo) | Esomeprazole magnesium (0.5-50 mg/kg; oral gavage; daily; for 10 days; A/J mice) treatment increases gastric total antioxidant capacity and Cu/Zn-superoxide dismutase activity[1].
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Clinical Trial | |||||||||||||||||
分子量 | 767.17 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C34H42MgN6O9S2 | ||||||||||||||||
CAS 号 | 217087-09-7 | ||||||||||||||||
中文名称 | 埃索美拉唑镁三水合物 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture and light *该产品在溶液状态不稳定,建议您现用现配,即刻使用。 | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 50 mg/mL(65.17 mM;Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液;该产品在溶液状态不稳定,建议您现用现配,即刻使用。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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