CAS NO: | 161796-84-5 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is a potent and orally activeproton pump inhibitorand reduces acid secretion through inhibition of theH+, K+-ATPasein gastric parietal cells. Esomeprazole potassium salt has the potential for symptomatic gastroesophageal reflux disease research[1][2][3]. | ||||||||
IC50& Target | H+, K+-ATPase[1][2] | ||||||||
体外研究 (In Vitro) | Esomeprazole (25-100 μM; 20 hours; MDA-MB-468 cells) treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification[1]. Cell Viability Assay[1]
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体内研究 (In Vivo) | Esomeprazole (30-300 mg/kg; oral gavage; daily; for 19 or 11 days; C57BL/6J mice) treatment significantly inhibits the progression of fibrosis throughout the lungs of the animals. Esomeprazole also reduces circulating markers of inflammation and fibrosis[2].
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Clinical Trial | |||||||||
分子量 | 383.51 | ||||||||
Formula | C17H18KN3O3S | ||||||||
CAS 号 | 161796-84-5 | ||||||||
中文名称 | 埃索美拉唑钾盐 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |