Esomeprazole ((S)-Omeprazole) hemistrontium is a potent and orally activeproton pumpinhibitor and reduces acid secretion through inhibition of theH⁺, K⁺-ATPasein gastric parietal cells. Esomeprazole hemistrontium has the potential for symptomatic gastroesophageal reflux disease research^[1][2][3].

Esomeprazole (25-100 μM; 20 hours; MDA-MB-468 cells) hemistrontium treatment suppresses growth of triple-negative breast cancer cell in vitro in a dose-dependent manner through increase in their intracellular acidification^[1].

Esomeprazole (30-300 mg/kg; oral gavage; daily; for 19 or 11 days; C57BL/6J mice) hemistrontium treatment significantly inhibits the progression of fibrosis throughout the lungs of the animals. Esomeprazole also reduces circulating markers of inflammation and fibrosis^[2].

388.22

C₁₇H₁₈N₃O₃SSr⁺

914613-86-8

埃索美拉唑锶

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.