Atorvastatin-d5 hemicalcium is the deuterium labeled Atorvastatin. Atorvastatin hemicalcium is an orally activeHMG-CoAreductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin hemicalcium inhibits human SV-SMC proliferation and invasion withIC₅₀s of 0.39 μM and 2.39 μM, respectively^[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

583.71

Solid

C₃₃H₃₀D₅FN₂O₅.1/2Ca

222412-82-0

阿托伐他汀 d5 (1/2钙盐)

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)