CJ-13,610 是一种非氧化还原型5-LO抑制剂,在没有外源性花生四烯酸的情况下,剂量依赖性地抑制离子载体 A23187 刺激的 PMNL 中 5-LO 产物的形成,IC50约为 70 nM。
生物活性 | CJ-13,610, a nonredox-type5-LOinhibitor, dose dependently suppresses 5-LO product formation in ionophore A23187-stimulated PMNL in the absence of exogenous AA with an IC50of about 70 nM[1]. PMNL: polymorphonuclear leukocytes; AA: arachidonic acid |
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运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |