BAPTA tetrapotassium is a selectivechelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca²⁺release from intracellular stores or influx via Ca²⁺-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibitphospholipaseCactivity independently of their role as Ca²⁺chelators^[1][2][4].

BAPTA (0.3-30 μM; 1 h) can be used for the prevention of [Ca²⁺]-induced cell damage, but disturbe calcium signalling in isingle differentiated NH15-CA2 neuroblastoma and glioma hybrid cells^[3].
BAPTA (0-10 mM) inhibits phospholipase C (PLC) activity in a dose-dependent manner, and is unrelated to Ca^2+[2].

628.79

C₂₂H₂₀K₄N₂O₁₀

73630-08-7

BAPTA四钾盐

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.