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Rocagloic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rocagloic acid图片
CAS NO:190385-15-0
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
Rocagloicacid是一种从Amooracucullata的果实中分离出来的具有有效细胞毒性的racaglamide衍生物。
Cas No.190385-15-0
Canonical SMILESO=C([C@H]([C@H]1C2=CC=CC=C2)[C@@H](O)[C@]3(O)[C@@]1(C4=CC=C(OC)C=C4)OC5=CC(OC)=CC(OC)=C35)O
分子式C27H26O8
分子量478.49
溶解度DMSO: 200 mg/mL (417.98 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Rocagloic acid is a racaglamide derivative isolated from the fruits of Amoora cucullata with potent cytotoxicity[1].

Rocagloic acid shows selective cytotoxicity against NCI-H187 cell line with an ED50 of 0.036 ng/mL, and is inactive against oral human epidermoid carcinoma (KB) and human breast cancer (BC) cells[1].

[1]. Parinuch Chumkaew, et al. Potent Cytotoxic Rocaglamide Derivatives From the Fruits of Amoora Cucullata. Chem Pharm Bull (Tokyo). 2006 Sep;54(9):1344-6.