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Saikosaponin C
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Saikosaponin C图片
CAS NO:20736-08-7
包装:20mg
市场价:1722元

产品介绍
Saikosaponin C 是一种存在于柴胡中的生物活性成分,针对阿尔茨海默病中的β淀粉样蛋白和 tau 蛋白。
Cas No.20736-08-7
别名柴胡皂苷 C
Canonical SMILESO[C@@H]1[C@H]2[C@](C(OC3)C(C)(C)C3C2)([H])[C@H]4[C@@]([C@@](CC[C@]5([H])[C@]6(C)CC[C@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@H]8O[C@@H](C)[C@H](O)[C@@H](O)[C@H]8O)[C@@H](CO[C@H]9[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O9)O7)C5(C)C)(C)[C@]6([H])C=C4)(C)C1
分子式C48H78O17
分子量927.12
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Saikosaponin C is a bioactive component found in radix bupleuri, targets amyloid beta and tau in Alzheimer's disease. Saikosaponin C inhibits the secretion of both Aβ1-40 and Aβ1-42, and suppresses abnormal tau phosphorylation, but shows no effect on BACE1 activity and expression[1].

References:
[1]. Lee TH1, et al. A potential therapeutic effect of saikosaponin C as a novel dual-target anti-Alzheimer agent. J Neurochem. 2016 Mar;136(6):1232-1245.