CAS NO: | 439153-64-7 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
20mg | 电议 |
Cas No. | 439153-64-7 |
别名 | (Rac)-LNK-754; (Rac)-OSI-754 |
Canonical SMILES | O=C1N(C)C2=C(C=C(C(O)(C3=CC=C(Cl)C=C3)C4=CN=CN4C)C=C2)C(C5=CC=CC(C#C)=C5)=C1 |
分子式 | C29H22ClN3O2 |
分子量 | 479.96 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | LNK754 is a farnesyltransferase inhibitor, used for the treatment of cancer and Alzheimer's disease. LNK-754 (0.9 mg/kg) significantly reduces α-synuclein plaques in a mouse model of PD, APP(SL), at 6 months of age for 3 months[1]. [1]. Keith T Gagnon. HD Therapeutics-CHDI Fifth Annual Conference. IDrugs. 2010 Apr;13(4):219-23. |