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GOAT-IN-1
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
GOAT-IN-1图片
CAS NO:1452473-54-9
包装与价格：
包装价格(元)
250mg电议
500mg电议

产品介绍
GOAT-IN-1是胃促生长素O-酰基转移酶(GOAT)的抑制剂，可用于预防或治疗肥胖、糖尿病、高脂血症、非酒精性脂肪肝、脂肪性肝炎、骨骼肌减少症、食欲控制、酒精/麻醉性依赖、阿尔茨海默症、帕金森、脑血管疾病与老年痴呆、脑卒中、脑梗死、心血管疾病、一些肿瘤等。
Cas No.1452473-54-9
Canonical SMILESCC1=NC(C(F)(F)F)=CC=C1COC2=CC(SC=C3CC(O)=O)=C3C(Cl)=C2
分子式C18H13ClF3NO3S
分子量415.81
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

GOAT-IN-1 is an inhibitor of ghrelin O-acyltransferase (GOAT), which could be useful for the prophylaxis or treatment of obesity, diabetes, hyperlipidemia, metabolic, non-alcoholic fatty liver, steatohepatitis, sarcopenia, appetite control, alcohol/narcotic dependence, Alzheimer's disease, Parkinson's disease, cerebrovascular dementia, cerebral apoplexy, cerebral infarction, cardic disease, some kind of tumors.

The inhibitory activity of GOAT-IN-1 (Example 16) for human GOAT is 101% with the concentration of 10 μM[1].

[1]. WO 2013125732.