CAS NO: | 1357362-02-7 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
500mg | 电议 |
生物活性 | Vafidemstat (ORY-2001) is an oral, brain penetrant, dual lysine-specifichistone demethylase(LSD1)/MAO-Binhibitor[1]. | ||||||||||||||||
IC50& Target | LSD1/MAO-B[1] | ||||||||||||||||
体外研究 (In Vitro) | Vafidemstat (ORY-2001), a dual LSD1/MAO-B inhibitor, is a novel epigenetic agent for the treatment of neurodegenerative diseases. LSD1 is a protein that participates in transcription regulation complexes; its modulation can be used to tweak transcriptional imbalances in neurodegenerative disease and redress neuroinflammation and cognitive deficit[1]. Vafidemstat (ORY-2001) can be used in the treatment of Alzheimer's disease[2]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 336.39 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C19H20N4O2 | ||||||||||||||||
CAS 号 | 1357362-02-7 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : 50 mg/mL(148.64 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
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