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Cimoxatone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cimoxatone图片
CAS NO:73815-11-9
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
MD 780515
产品介绍
Cimoxatone (MD 780515) 是一种可逆的口服活性 A 型单胺氧化酶 (MAO-A) (type A monoamine oxidase (MAO-A)) 抑制剂。Cimoxatone 增强type A monoamine oxidase (MAO-A)的厌食作用。
生物活性

Cimoxatone (MD 780515) is a reversible, selectively and orally activetype Amonoamine oxidase(MAO-A)inhibitor. Cimoxatone enhances the anorectic action ofSerotonin(HY-B1473A)[1].

IC50& Target[1]

MAO-A

 

体内研究
(In Vivo)

Cimoxatone (20 mg/kg; p.o.) 增强 5-HT (1 mg/kg; s.c.) 对大鼠的厌食作用[1]

Animal Model:250-300 g, Adult male Wistar rats[1]
Dosage:20 mg/kg
Administration:P.o.
Result:Significiantly reduced sucrose intake induced by 1 mg/kg 5-HT or its vehicle injected 2 and 24 h later, significantly enhanced the anorectic action of 5-HT at 2 h but not at 24 h.
分子量

338.36

Formula

C19H18N2O4

CAS 号

73815-11-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.