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Nalidixic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nalidixic acid图片
CAS NO:389-08-2
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
萘啶酸是一种喹诺酮类抗生素,对革兰氏阳性菌和革兰氏阴性菌均有效。
Cas No.389-08-2
别名萘啶酸
化学名1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
Canonical SMILESCCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O
分子式C12H12N2O3
分子量232.24
溶解度0.5 M NaOH: 50 mg/ml,Acetonitrile: >1 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum.Target: AntibacterialNalidixic acid is the first of the synthetic quinolone antibiotics. Nalidixic acid is effective against both gram-positive and gram-negative bacteria. In lower concentrations, it acts in a bacteriostatic manner; that is, it inhibits growth and reproduction. In higher concentrations, it is bactericidal, meaning that it kills bacteria instead of merely inhibiting their growth. Nalidixic selectively and reversibly blocks DNA replication in susceptible bacteria. Nalidixic acid and related antibiotics inhibit a subunit of DNA gyrase and topoisomerase IV and induce formation of cleavage complexes. It also inhibits the nicking-closing activity on the subunit of DNA gyrase that releases the positive binding stress on the supercoiled DNA. From Wikipedia.

References:
[1]. http://en.wikipedia.org/wiki/Nalidixic_acid