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Tylosin tartrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tylosin tartrate图片
CAS NO:74610-55-2
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议
1g电议
5g电议

产品介绍
Tylosin tartrate 是一种大环内酯类抗生素,天然存在于 Streptomyces fradiae 的发酵产物中。
Cas No.74610-55-2
别名酒石酸泰乐菌素
Canonical SMILESCCC1C(C=C(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)O)(C)O)N(C)C)O)CC=O)C)C)COC4C(C(C(C(O4)C)O)OC)OC.C(C(C(=O)O)O)(C(=O)O)O
分子式C46H77NO17.C4H6O6
分子量1066.19
溶解度≥ 36.85mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tylosin tartrate is an antibiotic with a large macrocyclic lactone ring.Target: AntibacterialTylosin tartrate is a bacteriostat food additive used in veterinary medicine. It has a broad spectrum of activity against gram-positive organisms and a limited range of gram-negative organisms. There is no significant evidence that tylosin resistant staphylococci of animal origin have endangered human health. Tylosin tartrate is not effective against the gram-negative intestinal flora, which thus does not lead to selection of R-factors by conjugation. From the human medical stand point, there is no reason that precludes the use of tylosin as a fee additive in animal feeds [1]. Minimum inhibitory concentrations for tylosin tartrate and other commonly used antibiotics were determined for 103 isolates. Most (82.61%) of the isolates not exposed to antibiotics in the 3 months before submission were sensitive to tylosin tartrate. These findings suggest that tylosin tartrate warrants further study as a first-line option for the treatment of dogs initially presenting with pyoderma [2].

References:
[1]. Knothe, H., A review of the medical considerations of the use of tylosin and other macrolide antibiotics as additives in animal feeds. Infection, 1977. 5(3): p. 183-7.
[2]. Scott, B.A., et al., Efficacy of tylosin tartrate on canine Staphylococcus intermedius isolates in vitro. Vet Ther, 2010. 11(3): p. E1-7.