您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Sodium 4-Aminosalicylate
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Sodium 4-Aminosalicylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sodium 4-Aminosalicylate图片
CAS NO:6018-19-5
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
4-氨基水杨酸钠(4-氨基水杨酸钠盐二水合物)是目前用于耐多药结核病的抗分枝杆菌药物之一。
Cas No.6018-19-5
别名对氨基水杨酸钠; 4-Aminosalicylic acid sodium salt dihydrate
化学名sodium;4-amino-2-hydroxybenzoate;dihydrate
Canonical SMILESC1=CC(=C(C=C1N)O)C(=O)[O-].O.O.[Na+]
分子式C7H7NO3.2H2O.Na
分子量211.15
溶解度≥ 10.65mg/mL in DMSO
储存条件4°C, protect from light, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sodium 4-aminosalicylate dihydrate is one of the antimycobacterial drugs currently used for multidrug-resistant tuberculosis.

References:
[1]. Zheng J, et al. para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis. J Biol Chem. 2013 Aug 9;288(32):23447-56.
[2]. Sy SK, et al. N-acetyltransferase genotypes and the pharmacokinetics and tolerability of para-aminosalicylic acid in drug-resistant pulmonary tuberculosis patients. Antimicrob Agents Chemother. 2015 May 11. pii: AAC.04049-14.