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Salicylanilide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Salicylanilide图片
CAS NO:87-17-2
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
Salicylanilide 具有广泛的生物活性,包括抗病毒效力,可通过靶向 HIV-1 整合酶或逆转录酶来抑制 HIV 病毒。
Cas No.87-17-2
别名水杨酰苯胺,2-Hydroxybenzanilide
化学名2-hydroxy-N-phenylbenzamide
Canonical SMILESC1=CC=C(C=C1)NC(=O)C2=CC=CC=C2O
分子式C13H11NO2
分子量213.23
溶解度≥ 8.8mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Salicylanilide demonstrates a wide range of biological activities including antiviral potency which can inhibit HIV virusby targeting HIV-1 integrase or reverse transcriptase.

Some Salicylanilides and salicylamides could inhibit HIV virus by targeting of HIV-1 integrase or reverse transcriptase. Hepatitis C virus is another virus, which can be potentially afflicted by Salicylanilides on the level of two enzymes-NS3 protease and NS5B RNA polymerase[1].

References:
[1]. Krátky M, et al. Antiviral activity of substituted salicylanilides--a review. Mini Rev Med Chem. 2011 Oct;11(11):956-67.