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Epoprostenol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Epoprostenol图片
CAS NO:61849-14-7
包装:10mg
市场价:7574元

产品介绍
依前列醇 (Prostaglandin I2 (sodium salt)) 是天然前列腺素衍生物前列环素 (prostaglandin I2) 的合成形式,已在全球范围内注册用于治疗肺动脉高压 (PAH)。
Cas No.61849-14-7
别名依前列醇钠,Prostaglandin I2 sodium salt; Prostacyclin sodium salt; Flolan
化学名sodium (E)-5-((3aR,4R,5R,6aS)-5-hydroxy-4-((S,E)-3-hydroxyoct-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-ylidene)pentanoate
Canonical SMILESO[C@H]1[C@H](/C=C/[C@H](CCCCC)O)[C@@H](C/2)[C@H](C1)OC2=C\CCCC([O-])=O.[Na+]
分子式C20H31NaO5
分子量374.45
溶解度DMF: 5 mg/ml,DMSO: 5 mg/ml,Ethanol: 10 mg/ml*,PBS (pH >10.2): 10 mg/ml,Water: 10 mg/ml
储存条件Desiccate at -80°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Epoprostenol sodium (Prostaglandin I2 (sodium salt)), the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH)[1]. Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation[2].

References:
[1]. Provencher S, et al.Quality of life, safety and efficacy profile of thermostable flolan in pulmonary arterialhypertension. PLoS One. 2015 Mar 20;10(3):e0120657.