CAS NO: | 128196-01-0 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
生物活性 | Escitalopram ((S)-Citalopram), the S-enantiomer of racemic Citalopram, is a selectiveserotonin reuptakeinhibitor (SSRI) with aKiof 0.89 nM. Escitalopram has ~30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over bothdopamine transporter(DAT) and norepinephrine transporter (NET). Escitalopram is an antidepressant for the research of major depression[1][2]. | ||||||||||||||||
IC50& Target | Ki: 0.89 nM (serotonin transporter), 10500 nM (DAT), 8150 nM (NET)[1] | ||||||||||||||||
体内研究 (In Vivo) | Escitalopram (10 mg/kg; i.p.; daily for 28 days) ameliorates cognitive impairments and selectively attenuates phosphorylated tau accumulation in stressed rats[3].
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Clinical Trial | |||||||||||||||||
分子量 | 324.39 | ||||||||||||||||
Formula | C20H21FN2O | ||||||||||||||||
CAS 号 | 128196-01-0 | ||||||||||||||||
中文名称 | 艾司西酞普兰;依他普仑;右旋西酞普兰;依地普伦 | ||||||||||||||||
结构分类 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |