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EPQpYEEIPIYL
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
EPQpYEEIPIYL图片
CAS NO:147612-86-0
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
50mg电议

产品介绍
EPQpYEEIPIYL 是一种磷酸肽,是 Src 同源 2 (SH2) 结构域配体。 EPQpYEEIPIYL 通过与 SH2 域结合来激活 Src 家族成员 (例如 Lck,Hck,Fyn)。
生物活性

EPQpYEEIPIYL, a phosphopeptide, is aSrchomology 2 (SH2) domain ligand. EPQpYEEIPIYL activatesSrcfamily members (e.g. Lck, Hck, Fyn) by binding to SH2 domains[1][2].

体外研究
(In Vitro)

The hmT-derived phosphopeptide, pY324, which has the sequence EPQpYEEIPIYL, shows the highest affinity binding to GST fusion proteins of the Lck SH2 domain (5-fold higher than Lck’s affinity-for the Lck tail phosphopeptide) and the Src SH2 domain (44-fold higher than Src’s affinity for the Src tail phosphopeptide)[1].

分子量

1473.52

性状

Solid

Formula

C66H97N12O24P

CAS 号

147612-86-0

Sequence Shortening

EPQpYEEIPIYL

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder-80°C2 years
-20°C1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O : 2 mg/mL(1.36 mM;ultrasonic and adjust pH to 2 with HCl)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM0.6786 mL3.3932 mL6.7865 mL
5 mM---------
10 mM---------
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。