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Dapansutrile
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dapansutrile图片
CAS NO:54863-37-5
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议

产品介绍
Dapansutrile(OLT1177)是有效,选择性和有口服活性的NLRP3炎性小体抑制剂。具有抗炎,镇痛活性。
Cas No.54863-37-5
Canonical SMILESN#CCCS(=O)(C)=O
分子式C4H7NO2S
分子量133.17
溶解度DMSO : ≥ 125 mg/mL (938.65 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Dapansutrile (OLT1177) is a potent, selective and orally active inhibitor of NLRP3 inflammasome. Anti-inflammatory, analgesic activity[1]. NLRP3 inflammasome[1]

[1]. Toldo S, et al. The NLRP3 Inflammasome Inhibitor, OLT1177 (Dapansutrile), Reduces Infarct Size and Preserves Contractile Function After Ischemia Reperfusion Injury in the Mouse. J Cardiovasc Pharmacol. 2019 Apr;73(4):215-222.