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3',4'-Dihydroxyflavonol
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3',4'-Dihydroxyflavonol图片
CAS NO:6068-78-6
包装:5mg
市场价:1440元

产品介绍
3',4'-Dihydroxyflavonol(DiOHF)是一种有效的抗氧化剂，可降低糖尿病大鼠肠系膜动脉中的超氧化物并改善NO功能。
Cas No.6068-78-6
别名3,3',4'-三羟基黄酮,DiOHF
Canonical SMILESO=C1C(O)=C(C2=CC=C(O)C(O)=C2)OC3=C1C=CC=C3
分子式C15H10O5
分子量270.24
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant, which reduces superoxide and improves nitric oxide (NO) function in diabetic rat mesenteric arteries[1].

3',4'-Dihydroxyflavonol (DiOHF) acutely preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS). DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling to improve endothelial function[1].3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²? desensitization in permeabilized third-order branches of rat mesenteric arteries[2].

[1]. Leo CH, et al. 3',4'-Dihydroxyflavonol reduces superoxide and improves nitric oxide function in diabetic rat mesenteric arteries. PLoS One. 2011;6(6):e20813. [2]. Kim HY, et al. 3',4'-Dihydroxyflavonol reduces vascular contraction through Ca²? desensitization in permeabilized rat mesenteric artery. Naunyn Schmiedebergs Arch Pharmacol. 2012 Feb;385(2):191-202.