ML 337 是一种选择性和脑渗透性的 mGlu3 负变构调节剂，IC50 为 593 nM。
| Cas No. | 1443118-44-2 |
| 化学名 | (R)-(2-fluoro-4-((4-methoxyphenyl)ethynyl)phenyl)(3-hydroxypiperidin-1-yl)methanone |
| Canonical SMILES | COC1=CC=C(C=C1)C#CC2=CC(F)=C(C(N3CCC[C@](O)([H])C3)=O)C=C2 |
| 分子式 | C21H20FNO3 |
| 分子量 | 353.39 |
| 溶解度 | <35.34mg/ml in DMSO;<7.07mg/ml in ethanol |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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