ML 289 (VU0463597) 是一种有效的、选择性的、可渗透 CNS 的 mGlu3 (IC50\u003d0.66 μM) 负变构调节剂。
| Cas No. | 1382481-79-9 |
| 别名 | VU0463597 |
| 化学名 | (R)-(3-(hydroxymethyl)piperidin-1-yl)(4-((4-methoxyphenyl)ethynyl)phenyl)methanone |
| Canonical SMILES | OC[C@@H]1CCCN(C(C2=CC=C(C#CC(C=C3)=CC=C3OC)C=C2)=O)C1 |
| 分子式 | C22H23NO3 |
| 分子量 | 349.42 |
| 溶解度 | DMSO: 10 mg/ml |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
m.cnreagent.com