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Secologanin
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Secologanin图片
CAS NO:19351-63-4
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Secologanin 是一种 secioridoid 糖苷，是生物合成具有生物活性的单萜吲哚生物碱（如利血平、阿马林和长春碱）中的关键萜类中间体。
Cas No.19351-63-4
别名断马钱子苷,NSC 640525
化学名(2S,3R,4S)-3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-(2-oxoethyl)-2H-pyran-5-carboxylic acid, methyl ester
Canonical SMILESOC[C@H]1O[C@@H](O[C@@]2([H])[C@H](C=C)[C@H](CC=O)C(C(OC)=O)=CO2)[C@H](O)[C@@H](O)[C@@H]1O
分子式C17H24O10
分子量388.4
溶解度Slightly soluble in water
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Secologanin is a monoterpene that has been found in V. rosea and is an intermediate in the synthesis of monoterpene indole alkaloids from geraniol. [1][2] It is a metabolite of loganin formed by the cytochrome P450 (CYP) isoform CYP72A1, also known as secologanin synthase.[3]

Reference:
[1]. Battersby, A.R., Burnett, A.R., and Parsons, P.G. Alkaloid biosynthesis. XIV. Secologanin: Its conversion into ipecoside and its role as biological precursor of the indole alkaloids. J. Chem. Soc. C Organic 8, 1187-1192 (1969).
[2]. Miettinen, K., Dong, L., Navrot, N., et al. The seco-iridoid pathway from Catharanthus roseus. Nat. Commun. 5:3606, (2014).
[3]. Irmler, S., Schroder, G., St-Pierre, B., et al. Indole alkaloid biosynthesis in Catharanthus roseus: New enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase. Plant J. 24(6), 797-804 (2000).