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Sel-green
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sel-green图片
CAS NO:1574299-37-8
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Sel-green是一种选择性的硒醇荧光探针,用于定量硒酶硫氧蛋白还原酶中的Sec含量,并对活细胞中的Sec进行荧光呈像。
Cas No.1574299-37-8
Canonical SMILESO=S(C1=CC=C([N+]([O-])=O)C=C1[N+]([O-])=O)(NC2=CC3=CC=C(N(CC)CC)C=C3OC2=O)=O
分子式C19H18N4O8S
分子量462.43
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sel-green, a selective selenol fluorescent probe, is applied to quantify the Sec content in the selenoenzyme thioredoxin reductase and image endogenous Sec in live HepG2 cells[1].

Sel-green displays >20-fold selectivity of Sec over DTT[1]. Sel-green is suitable for identifying the selenol species metabolized from various selenocompounds in cells, which helps to clarify the mechanism underlying the cytotoxicity of different selenocompounds[1].

[1]. Baoxin Zhang, et al. Selective selenol fluorescent probes: design, synthesis, structural determinants, and biological applications. J Am Chem Soc. 2015 Jan 21;137(2):757-69.