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4',5-Dihydroxyflavone
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
4',5-Dihydroxyflavone图片
CAS NO:6665-67-4
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议

产品介绍
4',5-Dihydroxyflavone是大豆LOX-1/α-glucosidase的抑制剂，其对大豆LOX-1的Ki值为102.6μM，对酵母α-glucosidase的IC50值为66μM。
Cas No.6665-67-4
别名5,4'-二羟基黄酮
Canonical SMILESO=C1C=C(C2=CC=C(O)C=C2)OC3=CC=CC(O)=C13
分子式C15H10O4
分子量254.24
溶解度DMSO : ≥ 155 mg/mL (609.66 mM);Water :< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase.

[1]. Ribeiro D, et al. Inhibition of LOX by flavonoids: a structure-activity relationship study. Eur J Med Chem. 2014 Jan 24;72:137-45. [2]. Proen?a C, et al. α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study. J Enzyme Inhib Med Chem. 2017 Dec;32(1):1216-1228.