| CAS NO: | 15183-37-6 |
| 包装 | 价格(元) |
| 500µg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 15183-37-6 |
| 别名 | 雌四醇 |
| 化学名 | estra-1,3,5(10)-triene-3,15α,16α,17β-tetrol |
| Canonical SMILES | OC1=CC(CC[C@]2([H])[C@]3([H])CC[C@@]4(C)[C@@]2([H])[C@@H](O)[C@@H](O)[C@@H]4O)=C3C=C1 |
| 分子式 | C18H24O4 |
| 分子量 | 304.4 |
| 溶解度 | 5mg/mL in ethanol, 20mg/mL in DMSO, 30mg/mL in DMF |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Estetrol is an estrogen steroid hormone exclusively produced by fetal liver from estradiol and estriol during pregnancy. It binds to estrogen receptors (ERs) with 4-fold higher affinity for ERα over ERβ and exhibits estrogenic effects in most tissues expressing ERs (bone, brain, vagina, and endometrium).[1],[2] In breast tumors, however, estetrol acts as an estrogen antagonist in the presence of estradiol, preventing tumor growth.[1],[2] Reference: [1]. Coelingh Bennink, H.J.T., Holinka, C.F., and Diczfalusy, E. Estetrol review: Profile and potential clinical applications Climacteric. 11(Suppl 1), 47-58 (2008). |
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