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Capreomycin Sulfate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Capreomycin Sulfate图片
CAS NO:1405-37-4
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
硫酸卷曲霉素是一种肽类抗生素,通常与氨基糖苷类一起使用,与其他抗生素联合用于治疗耐多药结核病。
Cas No.1405-37-4
别名硫酸卷曲霉素
Canonical SMILESO=C([C@]([H])(C)NC([C@](N)([H])CNC1=O)=O)N[C@@]([H])(CNC(CC(CCCN)N)=O)C(NC(C(N[C@@]1([H])[C@@H]2CCNC(N)=N2)=O)=CNC(N)=O)=O.[xH2SO4]
分子式C25H44N14O7.H2SO4
分子量750.78
溶解度≥ 251.8mg/mL in Water,<7.51mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Capreomycin sulfate is a peptide antibiotic, commonly grouped with the aminoglycosides, which is given in combination with other antibiotics for MDR-tuberculosis.IC50 value:Target: The drug should not be given with streptomycin or other drugs that may damage the auditory vestibular nerve. Patients on this drug will often require audiology tests. It is a cyclic peptide.Capreomycin is administered intramuscularly and shows bacteriostatic activity.

References:
[1]. Johansen SK, et al. Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2'-O-methylations in 16S and 23S rRNAs. Mol Cell. 2006 Jul 21;23(2):173-82.