Maydispenoid A is a potent immunosuppressor. Maydispenoid A can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation^[1].

Maydispenoid A (compound 2) exhibits potential inhibitory activity in anti-CD3/anti-CD28 monoclonal antibodies (mAbs) stimulated murine splenocytes proliferation, with an IC₅₀value of 5.28 μM, respectively^[1].
Maydispenoid A suppresses the murine splenocytes proliferation activated by lipopolysaccharide (LPS), with an IC₅₀value of 7.25 μM, respectively^[1].

416.59

C₂₆H₄₀O₄

• Terpenoids
• Sesquiterpenes

• Plants
• Salicaceae

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